What Is SS-31? How It Works + Why It Beats MOTS-C

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What Is SS-31 and How Does It Work in Your Mitochondria?

The protein that carries electrons through your mitochondria to make your energy or ATP can start attacking the wall it actually sits on, and SS-31 is the peptide that keeps it on the job, which is really the whole mechanism packed into one idea. So let me give you exactly what SS-31 is, what it actually does, and why that matters for you.

SS-31 is a synthetic peptide made of four amino acids, and it was designed to go straight to your mitochondria and concentrate there.

You see, your mitochondria, they make energy on an assembly line called the electron transport chain, and that electron transport chain sits on the inner wall of your mitochondria in a place called your cardiolipin. Electrons get passed down that line from one station to the next, and your cardiolipin is what's responsible for holding all that together.

Think of cardiolipin as the floor the machinery is bolted to. If the floor warps, the machines fall out of alignment, and the line slows down even though every individual machine still works.

Now, one part of that line is a carrier called cytochrome C, and cytochrome C's job is to move electrons between those stations and the electron transport chain.

But over time, those electrons can fall off of that assembly line and create what are called free radicals, and they build up with age. Once that buildup reaches a certain point, cytochrome C stops shuttling electrons and starts chewing on the cardiolipin underneath it instead, which warps the floor further, which makes more electrons leak, which makes more free radicals, and the whole cycle keeps feeding itself worse each time it spins.

So when you inject it, SS-31 actually gets pulled straight to that cardiolipin to bind them. It does not need a receptor and it does not need a transporter, because the charge on the peptide and the charge on the cardiolipin pull it in. Its job from there is to hold cytochrome C in place as an electron carrier instead of letting it turn on the wall.

As you age, as you experience metabolic stress, and if you fail to take care of your body, more electrons leak off of your electron transport chain. And SS-31 is doing the structural repair work on the cardiolipin to keep that line running clean.

But SS-31 can only fix the damage that's there, and most people miss that detail entirely. In a young body with a clean electron transport chain, there is not much for the peptide to grab onto, and you are paying for repair work on a floor that is already level. But the more damage that's built up over the years, the more SS-31 has to work on.

And that's exactly why when you take SS-31, you might not feel a buzz or anything different the first couple of days, but the longer you take it, the more time it has to repair that damaged structure. There is no acute rush or stimulant kick to notice, because you are rebuilding a surface, and surfaces rebuild slowly.

And that actually answers the biggest question people have with SS-31, which is whether you need to take it before you take MOTC. Well, you can kind of consider SS-31 as the cleanup crew. It fixes the machinery you already have, where MOTS-c is the construction team telling your body to build new mitochondria.

But the more interesting thing is that MOTC has recently been shown to actually go into the nucleus and trigger the repair of those cells in a different way. So you don't necessarily have to run SS-31 first.

But if years of damage are your problem, that repair can be greatly expedited by SS-31. So in this case, they're not necessarily competing, and you don't have to order them SS-31 and MOTC first. You can actually take them together, dependent upon your specific situation, your age, and how well you've taken care of your body.