Why Your Lipid Panel Doesn't Matter on Gear (ApoB + hs-CRP)
Watch the full video on Rumble: https://rumble.com/v7h32qk-why-your-lipid-panel-doesnt-matter-on-gear-apob-hs-crp.html
Why Your Lipid Panel Doesn't Matter on Gear: ApoB and hs-CRP Are the Only Two Numbers Worth Reading
If you're on anabolic steroids and your lipids are fucked up, my guess is your HDL is probably on the low end, your LDL is through the fucking ceiling, and if you're a fat ass, you've got triglycerides that are blowing out of every fucking gasket. That panel scares people into statins even though the standard lipid panel was never built to answer the question you're actually asking.
The panel measures cholesterol concentration, meaning how much cholesterol is floating around inside the particles that carry it through your blood, and it tells you almost nothing about how many of those particles there are or what kind of shape they're in.
Cholesterol doesn't damage an artery wall by existing in the blood, and that gap between concentration and actual damage is the whole thing you need to understand. It damages an artery wall when a particle carrying it physically wedges into the lining of the vessel, gets stuck there, oxidizes, and triggers an immune response that builds plaque over years.
So the number that matters is particle count, not cargo volume. Two men can have identical LDL cholesterol where one is carrying it in a small number of large particles and the other is carrying it in a huge number of small ones, and only the second man is driving particles into his artery walls at a high rate.
ApoB is apolipoprotein B, which is a protein that sits on the surface of every single atherogenic particle at a ratio of exactly one per particle, so measuring it gives you a direct headcount of how many things in your bloodstream are capable of lodging in an artery, and that headcount is exactly what the number captures.
The only things that exist that really matter as far as your labs are concerned are your APOB and your HSCRP. APOB is going to tell you the quality of the LDL, it's gonna tell you the quality of the blood lipids and where you stand with that, and if you're actually at a risk, your HSCRP is going to give you a picture of what your overall systemic inflammation is.
A particle has to stick to get in before it can do any damage, which is the second condition that has to be met alongside particle count, and it sticks far more readily when the endothelium, the single-cell lining of your blood vessels, is already irritated and expressing adhesion molecules.
And in all of the research that we've actually done to predict cardiac related events, it's a combination of high APOB with high HSCRP. Picture a highway where ApoB is traffic volume and hs-CRP is how torn up the road surface is. Heavy traffic moves fine across smooth pavement, but that same volume on a road full of potholes is where the pileup happens.
If we mitigate these things and we manage those and focus on getting that down, which mostly comes with managing insulin resistance and making sure you're eating healthy, whole foods, not processed junk, nine times out of 10, you don't really have a problem even with the high LDL. Now I could do a history lesson and go back to like the 70s or even before, like big pharma and the FDA got involved with telling you what your cholesterol should be, but high LDL is good.
Your brain uses it, your body uses it in a way that is going to help you continue to function effectively, especially as far as your metabolic health is concerned. Cholesterol is the raw material your body converts into testosterone, cortisol and vitamin D, and a quarter of all the cholesterol in your body sits in your brain holding cell membranes together.
There is a lot more of this inside the free community, and it is genuinely free, so if you want somewhere to ask the follow-up question the men's group is here: https://www.skool.com/jh-iron-forge-brotherhood/about
If this is the kind of information you want access to on a daily basis, the community is free and there are full courses on training, nutrition, hormones, and supplementation inside. You can ask questions and post your own labs and get feedback from me and from the community.