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Research backed education on training, nutrition, hormones, and supplementation, written to go deeper than a video can.
Your body does not make testosterone in one step. It runs through a signaling chain that starts in your brain and ends at specialized cells in your testes called Leydig cells, which are the actual manufacturing site where cholesterol ge...
Your thyroid produces two hormones, but only one of them actually does anything. T4, called thyroxine, makes up about 80% of what your thyroid gland releases into circulation. T3, called triiodothyronine, makes up the remaining 20%. T4 ...
Your mitochondria are running two separate maintenance systems at the same time, and most people have no idea those systems even exist, let alone that they can be supported simultaneously. One system is structural. The inner membrane of...
Your body does not care that you are trying to lose weight. It only knows what it feels like right now, and if a drug makes it feel bad right now, it is going to resist. That is the core problem with retatrutide side effects, and why ma...
Aromatase is an enzyme, something called CYP19A1, that converts testosterone into estradiol. That one sentence explains almost every estrogen problem men run into on TRT, and almost every mistake providers make when trying to fix those ...
The common belief about training volume is that more sets equal more muscle, and there is a version of that which is correct. A large systematic review and meta-analysis looked at the relationship between weekly set volume and muscle gr...
Your doctor looked at one number and said everything was fine. That number was almost certainly total testosterone, and the problem is that total testosterone tells you how much testosterone is in your bloodstream, not how much your bod...
The fear around testosterone replacement therapy and heart attacks did not come from nowhere. It came from real studies, published in real journals, that showed real associations between testosterone use and cardiovascular events. The p...
The fear of testosterone and prostate cancer traces back to a single experiment from 1941, and understanding why that experiment was misread explains almost everything about this topic. A researcher named Huggins took men who had alread...
Testosterone is not a single number your body locks in and leaves alone. It rises and falls constantly based on signals your body is receiving, and two of the most powerful suppressors of that number are aromatase and cortisol. Aromatas...
Your kidneys filter your blood constantly, and one of the things they pull out is a waste product called creatinine, which is what your body produces when it breaks down creatine. The rate at which your kidneys clear creatinine from you...
Cardarine shows up in a lot of conversations about fat loss and endurance, and the discussion almost always collapses into two opposing camps. One side says it causes cancer. The other side says the doses in the animal studies were so e...
